Anthelmintic Activity of Shell Extract of Selected Seeds

Moushumi Baidya*¹, J. Anbu²

*1Department of Pharmacology, Faculty of Pharmacy, Brainware University, Barasat, West Bengal, India.

2Department of Pharmacology, Faculty of Pharmacy, Ramaiah University, Bangalore, Karnataka, India.

Correspondence: Email- baidyamoushumi@gmail.com

Abstract

Objective: The study was undertaken to evaluate the phytochemical study and anthelmintic activity of ethanolic extract of polyherbal seed shells (EEPSS) against Eisenia fatida.

Methods: The seed of Momordica charantia, Manilkara zapota, Emblica officinalis and Syzygium cumini collected from the local market, Bangalore, India. EEPSS was prepared from the dried seed shells of four different fruits using the solvent ethanol. Initially, EEPSS was screened for phytochemical constituents by standard protocol. Further, anthelmintic study was conducted against Eisenia fatida, collected from local Vermicomposting Farm, Bangalore.

Results: In the phytochemical screening, the EEPSS showed presence of glycosides, alkaloids, flavonoids, phenols, phytosterols and tannins. In the anthelmintic study, mortality was produced in earth worm populations by EEPSS.

Conclusion: The use of EEPSS as an anthelmintic was confirmed by using standard method against Eisenia fatida. The results indicated that the test drug has significant anthelmintic properties. Hence, it can be concluded that the EEPSS can be used as a novel drug for the treatment of worm infestations.

Keywords: EEPSS, Phytochemical screening, Eisenia fatida, Helminthiasis